Kaiser Permanente Irvine Medical Center and Medical Office Building 1 and 2 (Irvine, CA) The first 110,000 square-foot medical office building was the commencement of this site back in 2004. It was a 4-story building and included a surgery center. The second medical office building was a 6-story, 145,000 square-foot structure designed in 2004 with its construction being completed in 2006. It housed a full imaging department and gastroenterology (GI) department, among others.